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DI-87

Product Specifications

UNSPSC Description

DI-87 is an orally active and selective deoxycytidine kinase (dCK) inhibitor with an EC50 of 10.2 nM. DI-87 has antitumor activity and is used in combination therapy against tumors expressing dCK[1].

Target Antigen

Others

Type

Reference compound

Related Pathways

Others

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/di-87.html

Smiles

NC1=NC(S[C@@H](C2=C(C)SC(C3=CC=C(OC)C(OCCN4CCOCC4)=C3)=N2)C)=NC(N)=C1

Molecular Weight

502.65

References & Citations

[1]Soumya Poddar, et al. Development and Preclinical Pharmacology of a Novel dCK Inhibitor, DI-87. Biochem Pharmacol. 2020 Feb;172:113742.

Shipping Conditions

Room Temperature

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-133141/DI-87-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-133141/DI-87-SDS-MedChemExpress.pdf

CAS Number

2107280-55-5

Available Sizes

Curated Selection

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