MDM2 Recombinant Mouse Monoclonal Antibody [A10E11-R]
Selected Variant
HA601310
Size: 100 µL
Mouse double minute 2 homolog (MDM2) also known as E3 ubiquitin-protein ligase Mdm2 is a protein that in humans is encoded by the MDM2 gene. Mdm2 is an important negative regulator of the p53 tumor suppressor. Mdm2 protein functions both as an E3 ubiquitin ligase that recognizes the N-terminal trans-activation domain (TAD) of the p53 tumor suppressor and as an inhibitor of p53 transcriptional activation.
Product Specifications
CAS Number
9000-83-3
Product Name Alternative
Abbreviation
MDM2
Swiss Prot
Q00987 Human
Cellular Locus
Nucleus, nucleoplasm, nucleolus, Cytoplasm.
Host
Mouse
Species Reactivity
Human, Monkey
Immunogen
Recombinant protein within human MDM2 aa 1-491 / 491.
Isotype
IgG1
Clone
A10E11-R
Conjugation
Non-conjugated
Type
Recombinant Mouse monoclonal Antibody
Applications
WB, IF-Cell, IHC-P
Positive Control
Concentration
1 mg/mL
Dilution
WB: 1:1,000 ;IF-Cell: 1:500 ;IHC-P: 1:1,000
Purity
Protein A affinity purified.
Form
Liquid
Buffer
PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 55 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
Yes
Price
Frequently Asked Questions
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