Paridiprubart
Paridiprubart (NI-0101) is a humanised anti-TLR4 monoclonal antibody. Paridiprubar inhibits the production of pro-inflammatory cytokines by monocytes from rheumatoid arthritis specimen induced by rheumatoid arthritis synovial fluid (RASF) . Paridiprubart can be used for the study of rheumatoid arthritis[1].
Product Specifications
CAS Number
[2641646-59-3]
Product Name Alternative
NI-0101
UNSPSC
12352203
Target
Toll-like Receptor (TLR)
Type
Inhibitory Antibodies
Related Pathways
Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/paridiprubart.html
Purity
95.0
Solubility
10 mM in DMSO
Smiles
[Paridiprubart]
Molecular Weight
(145.16 kDa)
References & Citations
[1]Hatterer E, et al. A specific anti-citrullinated protein antibody profile identifies a group of rheumatoid arthritis patients with a toll-like receptor 4-mediated disease. Arthritis Res Ther. 2016 Oct 6;18 (1) :224.
Shipping Conditions
Dry Ice
Storage Conditions
Store at -80°C for 2 years
Scientific Category
Inhibitory Antibodies
Clinical Information
Phase 2
Available Sizes
Curated Selection
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