Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

L-Ascorbic acid (Standard)

L-Ascorbic acid (Standard) is the analytical standard of L-Ascorbic acid. This product is intended for research and analytical applications. L-Ascorbic acid (L-Ascorbate), an electron donor, is an endogenous antioxidant agent. L-Ascorbic acid inhibits selectively Cav3.2 channels with an IC50 of 6.5 μM. L-Ascorbic acid is also a collagen deposition enhancer and an elastogenesis inhibitor[1][2][3]. L-Ascorbic acid exhibits anti-cancer effects through the generation of reactive oxygen species (ROS) and selective damage to cancer cells[4].

Product Specifications

CAS Number

50-81-7

Product Name Alternative

L-Ascorbate (Standard) ; Vitamin C (Standard)

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Apoptosis; Calcium Channel; Endogenous Metabolite; Reactive Oxygen Species (ROS) ; Reference Standards

Type

Reference Standards

Related Pathways

Apoptosis; Immunology/Inflammation; Membrane Transporter/Ion Channel; Metabolic Enzyme/Protease; Neuronal Signaling; NF-κB; Others

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Cancer; Metabolic Disease; Neurological Disease

Assay Protocol

https://www.medchemexpress.com/l-ascorbic-acid-standard.html

Purity

99.97

Solubility

DMSO : 116.67 mg/mL (ultrasonic)

Smiles

OC([C@@]1([H])[C@H](CO)O)=C(O)C(O1)=O

Molecular Formula

C6H8O6

Molecular Weight

176.12

Precautions

H302, H315, H319, H335

References & Citations

[1]Sebastian J Padayatty, et al. Vitamin C as an antioxidant: evaluation of its role in disease prevention. J Am Coll Nutr. 2003 Feb;22 (1) :18-35.|[2]Michael T Nelson, et al. Molecular mechanisms of subtype-specific inhibition of neuronal T-type calcium channels by ascorbate. J Neurosci. 2007 Nov 14;27 (46) :12577-83.|[3]Aleksander Hinek, et al. Sodium L-ascorbate enhances elastic fibers deposition by fibroblasts from normal and pathologic human skin. J Dermatol Sci. 2014 Sep;75 (3) :173-82.|[4]Sungrae Cho, et al. Hormetic dose response to L-ascorbic acid as an anti-cancer drug in colorectal cancer cell lines according to SVCT-2 expression. Sci Rep. 2018 Jul 27;8 (1) :11372.|[5]Satyanarayana Sreemantula, et al. Influence of antioxidant (L- ascorbic acid) on tolbutamide induced hypoglycaemia/antihyperglycaemia in normal and diabetic rats. BMC Endocr Disord. 2005 Mar 3;5 (1) :2.

Shipping Conditions

Room Temperature

Storage Conditions

4°C, sealed storage, away from light and moisture

Scientific Category

Reference Standards

Clinical Information

Launched

Available Sizes

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

HIF1AN/FIH-1 Antibody [N1M12]
F3149-100uL*2 2x 100 μL

HIF1AN/FIH-1 Antibody [N1M12]

Sign In for Pricing
View Details
MGC40574 Lentiviral Vector (Human) (EF1a) (pLenti-GIII-EF1a)
LV810218 1.0 µg DNA

MGC40574 Lentiviral Vector (Human) (EF1a) (pLenti-GIII-EF1a)

Sign In for Pricing
View Details
NFS1 Antibody
orb1267582 400 μl

NFS1 Antibody

Sign In for Pricing
View Details
EIF2S2P5 ORF Vector (Human) (pORF)
ORF018793 1.0 µg DNA

EIF2S2P5 ORF Vector (Human) (pORF)

Sign In for Pricing
View Details
NOL4, CT (NOL4, NOLP, Nucleolar protein 4, Nucleolar-localized protein) (MaxLight 550) discontinued
039050-ML550 100 µL

NOL4, CT (NOL4, NOLP, Nucleolar protein 4, Nucleolar-localized protein) (MaxLight 550) discontinued

Sign In for Pricing
View Details
MEG2, CT (Tyrosine-protein phosphatase, non-receptor type 9, Protein-tyrosine phosphatase MEG2, PTPase-MEG2) (Azide free) (HRP)
MBS6495756-01 0.2 mL

MEG2, CT (Tyrosine-protein phosphatase, non-receptor type 9, Protein-tyrosine phosphatase MEG2, PTPase-MEG2) (Azide free) (HRP)

Sign In for Pricing
View Details