GAD65 (524-543)
GAD65 (524-543) is a biological active peptide with amino acids 524 to 543 fragment of glutamic acid decarboxylase 65 (GAD65) . GAD65 (524-543) is one of the first fragments of islet antigen to induce proliferative T cell responses in the non-obese diabetic (NOD) mouse model of spontaneous autoimmune diabetes. GAD65 (524-543) is a specific, possibly low affinity, stimulus for the spontaneously arising diabetogenic T cell clone BDC2.5. Immunization with GAD65 (524-543) increases the susceptibility of the NOD mice to type 1 diabetes induced by the adoptive transfer of BDC2.5 T cells[1].
Product Specifications
CAS Number
[152468-44-5]
UNSPSC
12352209
Target
Amino Acid Decarboxylase
Type
Peptides
Related Pathways
Neuronal Signaling
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/gad65-524-543.html
Solubility
10 mM in DMSO
Smiles
Molecular Formula
C97H168N28O28S2
Molecular Weight
2238.67
References & Citations
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported
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