(2R) -Flavanomarein

(2R) -Flavanomarein is a predominant flavonoid of Coreopsis tinctoria Nutt with protective effects against diabetic nephropathy. (2R) -Flavanomarein has good antioxidative, antidiabetic, antihypertensive and anti-hyperlipidemic activities[1][2].

Product Specifications

CAS Number

[56389-87-8]

UNSPSC

12352005

Target

Others

Type

Natural Products

Related Pathways

Others

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/2r-flavanomarein.html

Solubility

10 mM in DMSO

Smiles

OC1=C2C(C(C[C@H](C3=CC(O)=C(C=C3)O)O2)=O)=CC=C1O[C@@H]4O[C@@H]([C@H]([C@@H]([C@H]4O)O)O)CO

Molecular Formula

C21H22O11

Molecular Weight

450.39

References & Citations

[1]Nan-Nan Zhang, et al. Flavanomarein inhibits high glucose-stimulated epithelial-mesenchymal transition in HK-2 cells via targeting spleen tyrosine kinase. Sci Rep. 2020 Jan 16;10 (1) :439.|[2]Liang Le, et al. The protective effects of the native flavanone flavanomarein on neuronal cells damaged by 6-OHDA. Phytomedicine. 2019 Feb;53:193-204.