Question 1

What is the catalog number for LC-2?

Accepted Answer

The catalog number for LC-2 is HY-137516.

Question 2

What sizes are available for LC-2?

Accepted Answer

LC-2 is available in the following size(s): 1 mg, 5 mg, 10 mg, 25 mg, 50 mg, 100 mg.

Question 3

How many pack sizes does LC-2 come in?

Accepted Answer

LC-2 is available in 6 different pack sizes.

Question 4

Is LC-2 in stock?

Accepted Answer

LC-2 is currently made to order / not held in immediate stock. Contact us for lead time.

Question 5

Who manufactures LC-2?

Accepted Answer

LC-2 is manufactured by QuantiMol.

Question 6

What is the estimated delivery time for LC-2?

Accepted Answer

Estimated delivery time for LC-2 is approximately 15 business day(s), depending on your location.

Question 7

Where can I find the safety data sheet (SDS/MSDS) for LC-2?

Accepted Answer

The safety data sheet for LC-2 is available here: http://file.medchemexpress.com/batch_PDF/HY-137516/LC-2-SDS-MedChemExpress.pdf.

Question 8

What is LC-2 used for?

Accepted Answer

LC-2 is a potent and first-in-class von Hippel-Lindau-based PROTAC capable of degrading endogenous KRAS G12C, with DC50s between 0.25 and 0.76 μM[1]. LC-2 covalently binds KRAS G12C with a MRTX849 warhead and recruits the E3 ligase VHL, inducing rapid and sustained KRAS G12C degradation leading to s

Question 9

Can you help me confirm if this product is right for my specific experiment?

Accepted Answer

Yes, contact us with details of your sample type, species, and intended application, and our specialists will confirm suitability or suggest an alternative from our supplier network if this isn’t the best fit.

Question 10

What is the purity of this recombinant protein?

Accepted Answer

Purity, typically assessed by SDS-PAGE, is listed on the datasheet under quality control data.

Question 11

What do I do if this product arrives with reduced ice or a damaged cold-chain package?

Accepted Answer

Report this to us immediately with photos and your order reference. Our specialists will assess whether the product is still usable given the cold-chain interruption, and will arrange a replacement or credit if it isn’t.

LC-2

Product Specifications

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Clinical Information

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Available Sizes

Frequently Asked Questions

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