Lalistat 1
Product Specifications
Product Name Alternative
AM152
UNSPSC Description
Lalistat 1 is a potent,?selective, and competitive inhibitor of lysosomal acid lipase (LAL) and against purified human LAL (phLAL) with an IC50 of 68 nM.?Lalistat 1 is a inhibitor of?immunoglobulin A1 protease (IgA1P) proteases for H. influenzae, has less effects on other serine hydrolases (trypsin or β-lactamase, etc.). Lalistat 1 can be used for the research of niemann-pick type C (NPC) disease[2].
Target Antigen
Bacterial; Beta-lactamase
Type
Reference compound
Related Pathways
Anti-infection
Field of Research
Infection; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/lalistat-1.html
Purity
99.85
Solubility
DMSO : 20 mg/mL (ultrasonic;warming)
Smiles
O=C(N1CCOCC1)OC2=NSN=C2N3CCCCC3
Molecular Weight
298.368
References & Citations
[1]Anton I Rosenbaum , et al. Thiadiazole carbamates: potent inhibitors of lysosomal acid lipase and potential Niemann-Pick type C disease therapeutics. J Med Chem . 2010 Jul 22;53(14):5281-9.|[2]Livia Shehaj, et al. Small-Molecule Inhibitors of Haemophilus influenzae IgA1 Protease.ACS Infect Dis. 2019 Jul 12;5(7):1129-1138.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-116815/Lalistat-1-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-116815/Lalistat-1-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
501104-16-1
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
