MSU38225
Product Specifications
UNSPSC Description
MSU38225 is an Nrf-2 inhibitor that increases levels of reactive oxygen species (ROS). MSU38225 inhibits the growth of human lung cancer cells and enhances the sensitivity of human lung cancer cells to chemotherapy in vitro and in vivo. MSU38225 can be used in cancer research[1].
Target Antigen
Keap1-Nrf2; Reactive Oxygen Species
Type
Reference compound
Related Pathways
Immunology/Inflammation;Metabolic Enzyme/Protease;NF-κB
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/msu38225.html
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
N#CC1=C(NC2=CC(C)=CC(C)=C2)N=C(C)C(C3=CC=CC=C3)=C1
Molecular Weight
313.40
References & Citations
[1]Zhang D, et al. A Novel Nrf2 Pathway Inhibitor Sensitizes Keap1-Mutant Lung Cancer Cells to Chemotherapy. Mol Cancer Ther. 2021 Sep;20(9):1692-1701.
Shipping Conditions
Blue Ice
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-153873/MSU38225-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-153873/MSU38225-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
1629160-83-3
Available Sizes
Curated Selection
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