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Human C5AR1 Protein, Flag, His Tag (Detergent)

Receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a.The ligand interacts with at least two sites on the receptor: a high-affinity site on the extracellular N-terminus, and a second site in the transmembrane region which activates downstream signaling events. Receptor activation stimulates chemotaxis, granule enzyme release, intracellular calcium release and superoxide anion production.

Product Specifications

Background

Receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a.The ligand interacts with at least two sites on the receptor: a high-affinity site on the extracellular N-terminus, and a second site in the transmembrane region which activates downstream signaling events. Receptor activation stimulates chemotaxis, granule enzyme release, intracellular calcium release and superoxide anion production.

Specifications

This protein carries a flag tag at the N-terminus and a polyhistidine tag at the C-terminus. The protein has a calculated MW of 37.4 kDa.

Accession Number

P21730-1

Expression Region

Ser 30 - Glu 331

Host

HEK293

Target

C5AR1

Conjugation

Unconjugated

Tag

N-Flag & C-10xHis

Source

Human

Stability

The product MUST be stored at -70°C or lower upon receipt; -70°C for 3 months under sterile conditions.

Endotoxin

1.0 EU per μg

Purity

90%

Bioactivity

Immobilized Human C5AR1 Protein, Flag,His Tag (Cat. No. C51-H52D3) at 2 μg/mL (100 μL/well) can bind Biosimilar Avdoralimab with a linear range of 0.06-4 ng/mL (QC tested).

Format

Liquid

Buffer

50 mM HEPES, 150 mM NaCl, DDM, CHS, pH7.5

Additives

Glycerol

Molecular Weight

37.4 kDa

Additionnal Information

Please see 'Shipping-and-Payments' sheet. Website: https://www.acrobiosystems.com/support/shipping-and-payments

Shipping Conditions

Dry ice

Storage Conditions

-70°C

Package Size

500ug*1

Host or Source

HEK293

Species

Human

Protein ID

P21730-1

Preservative

Glycerol

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