5a-Pregnane-3,20-dione-d6
5a-Pregnane-3,20-dione-d6 is the deuterium labeled 5a-Pregnane-3,20-dione. 5a-Pregnane-3,20-dione is the endogenous progesterone metabolite.
Product Specifications
CAS Number
203850-92-4
UNSPSC
12352211
Target
Endogenous Metabolite
Type
Isotope-Labeled Compounds
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Endocrinology; Cancer
Purity
99.0
Solubility
10 mM in DMSO|DMSO : 6.67mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
C[C@@]12[C@]3([H])[C@](C([2H])C([2H])[C@@]1([2H])C([2H])C(C([2H])C2[2H])=O)([H])[C@@]4([H])[C@](CC3)([C@H](CC4)C(C)=O)C
Molecular Formula
C21H26D6O2
Molecular Weight
322.51
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216. |[2]Wiebe JP, et al. The endogenous progesterone metabolite, 5a-pregnane-3,20-dione, decreases cell-substrate attachment, adhesion plaques, vinculin expression, and polymerized F-actin in MCF-7 breast cancer cells. Endocrine. 2001 Oct;16 (1) :7-14.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
BNC040225-500 1x 500 µL
Major Vault Protein (MVP) (1032), CF405S conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC400012-100 1x 100 µL
Tyrosinase (T311), CF640R conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC880525-500 1x 500 µL
CD63 (MX-49.129.5), CF488A conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC680734-100 1x 100 µL
TAG-72 / CA72.4 (B72.3 + CA72/733), CF568 conjugate, 0.1mg/mL
Sign In for Pricing
View Details