p38-α MAPK-IN-1

p38-α MAPK-IN-1 is an inhibitor of MAPK14 (p38-α), with IC50 of 2300 nM in EFC displacement assay, and 5500 nM in HTRF assay[1].

Autophagy; p38 MAPK

Reference compound

Autophagy;MAPK/ERK Pathway

Others

https://www.medchemexpress.com/p38-_alpha__MAPK-IN-1.html

99.89

DMSO : 100 mg/mL (ultrasonic)

CC1=CC=C(N2C(NC(NC3=CC=C(OCCN4CCOCC4)C=C3)=O)=CC(C(C)(C)C)=N2)C=C1

477.60

[1]Kluter S, et al. Displacement assay for the detection of stabilizers of inactive kinase conformations. J Med Chem. 2010 Jan 14;53(1):357-67.

Room Temperature

-20°C, 3 years; 4°C, 2 years (Powder)

http://file.medchemexpress.com/batch_PDF/HY-18874/p38-α-MAPK-IN-1-DataSheet-MedChemExpress.pdf

http://file.medchemexpress.com/batch_PDF/HY-18874/p38-α-MAPK-IN-1-SDS-MedChemExpress.pdf

No Development Reported

443913-15-3