p38-α MAPK-IN-1
Product Specifications
UNSPSC Description
p38-α MAPK-IN-1 is an inhibitor of MAPK14 (p38-α), with IC50 of 2300 nM in EFC displacement assay, and 5500 nM in HTRF assay[1].
Target Antigen
Autophagy; p38 MAPK
Type
Reference compound
Related Pathways
Autophagy;MAPK/ERK Pathway
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/p38-_alpha__MAPK-IN-1.html
Purity
99.89
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
CC1=CC=C(N2C(NC(NC3=CC=C(OCCN4CCOCC4)C=C3)=O)=CC(C(C)(C)C)=N2)C=C1
Molecular Weight
477.60
References & Citations
[1]Kluter S, et al. Displacement assay for the detection of stabilizers of inactive kinase conformations. J Med Chem. 2010 Jan 14;53(1):357-67.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-18874/p38-α-MAPK-IN-1-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-18874/p38-α-MAPK-IN-1-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
443913-15-3
Available Sizes
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