Salermide
Salermide is an inhibitor of Sirt1 and Sirt2; can cause strong cancer-specific apoptotic cell death.
Product Specifications
CAS Number
[1105698-15-4]
UNSPSC
12352005
Hazard Statement
H317, H412
Target
Apoptosis; Sirtuin
Type
Reference compound
Related Pathways
Apoptosis; Cell Cycle/DNA Damage; Epigenetics
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/Salermide.html
Purity
98.0
Solubility
DMSO : ≥ 50 mg/mL
Smiles
O=C(NC1=CC=CC(/N=C/C2=C3C=CC=CC3=CC=C2O)=C1)C(C)C4=CC=CC=C4
Molecular Formula
C26H22N2O2
Molecular Weight
394.47
Precautions
H317, H412
References & Citations
[1]Lara E, et al. Salermide, a Sirtuin inhibitor with a strong cancer-specific proapoptotic effect. Oncogene. 2009 Feb 12;28 (6) :781-91.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
SIRT1; SIRT2
Available Sizes
Curated Selection
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