M4284
M4284 is a selective and orally active biphenyl mannoside FimH antagonist. M4284 has activities against different UPEC (Urinary tract infections (UTI) caused by uropathogenic E. coli) strains in different host genetic backgrounds and gut microbial community contexts[1].
Product Specifications
CAS Number
[1373346-85-0]
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
Bacterial
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/m4284.html
Purity
98.15
Solubility
DMSO : 125 mg/mL (ultrasonic)
Smiles
O=C(C1=CC(C(NC)=O)=CC(C2=CC=C(O[C@@H]3[C@H]([C@H]([C@@H]([C@@H](CO)O3)O)O)O)C(C)=C2)=C1)NC
Molecular Formula
C23H28N2O8
Molecular Weight
460.48
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]Schaeffer EM, et al.Selective Depletion of Uropathogenic E. coli from the Gut by a FimH Antagonist.SelectivJ Urol. 2018 Apr;199 (4) :874-875.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
Recombinant Bacillus halodurans Lipoyl synthase (lipA)
Recombinant Bacillus halodurans Lipoyl synthase (lipA)
