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L-Gulono-1,4-lactone

L-Gulono-1,4-lactone is a substrate of L-gulono-1,4-lactone oxidoreductase, which catalyzes the last step of the biosynthesis of L-ascorbic (Vatamin) C. In other words, L-Gulono-1,4-lactone is a direct precursor of vitamin C in animals, in plants and in some protists.

Product Specifications

CAS Number

[1128-23-0]

Product Name Alternative

L-Gulonolactone

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Endogenous Metabolite

Type

Natural Products

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/_3S,4R,5R_-5-__S_-1,2-Dihydroxyethyl_-3,4-dihydroxydihydrofuran-2_3H_-one.html

Purity

99.70

Solubility

H2O : 50 mg/mL (ultrasonic)

Smiles

O=C1O[C@H]([C@@H](O)CO)[C@H](O)[C@@H]1O

Molecular Formula

C6H10O6

Molecular Weight

178.14

Precautions

H302, H315, H319, H335

References & Citations

[1]Wolucka BA, et al. Mycobacterium tuberculosis possesses a functional enzyme for the synthesis of vitamin C, L-gulono-1,4-lactone dehydrogenase. FEBS J. 2006 Oct;273 (19) :4435-45. Epub 2006 Sep 5.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Natural Products

Clinical Information

No Development Reported

Isoform

Human Endogenous Metabolite

Available Sizes

Curated Selection

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