STING agonist-12
STING agonist-12 (Compound 53) is a potent, orally active human STING activator with an EC50 of 185 nM[1].
Product Specifications
CAS Number
2259624-71-8
UNSPSC
12352005
Target
STING
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/sting-agonist-12.html
Concentration
10mM
Purity
98.26
Solubility
DMSO : 250 mg/mL (ultrasonic)
Smiles
ClC1=CC=CC(F)=C1CN2C3=C(C(C)(C2=O)C)C=CC(C(NCC4=C(C=C(C=C4F)F)F)=O)=C3
Molecular Formula
C25H19ClF4N2O2
Molecular Weight
490.88
References & Citations
[1]Pryde DC, et al. The discovery of potent small molecule activators of human STING. Eur J Med Chem. 2021 Jan 1;209:112869.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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