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DKK-1, Cynomolgus/Rhesus Macaque (HEK293, His)

DKK-1 Proteinas are potent antagonists of canonical Wnt signaling, inhibiting LRP5/6-Wnt interactions and forming a ternary complex with KREMEN to promote LRP5/6 internalization. In addition to its proapoptotic function by antagonizing KREMEN1 independently of Wnt, DKK-1 also exhibits antiapoptotic activity. DKK-1 Protein, Cynomolgus/Rhesus Macaque (HEK293, His) is the recombinant cynomolgus/rhesus macaque-derived DKK1 protein, expressed by HEK293, with C-His labeled tag.

Product Specifications

Product Name Alternative

DKK-1 Protein, Cynomolgus/Rhesus Macaque (HEK293, His), Cynomolgus; Rhesus Macaque, HEK293

UNSPSC

12352202

Type

Reference compound

Assay Protocol

https://www.medchemexpress.com/cytokines/dkk1-protein-cynomolgus-rhesus-macaque-hek293-his.html

Purity

95.0

Molecular Formula

702997/102123735 (Gene_ID) XP_005565907.1/NP_001247454.1 (T32-H266) (Accession)

Molecular Weight

Approximately 40-50 kDa, based on SDS-PAGE under reducing conditions, due to the glycosylation.

Shipping Conditions

Room temperature in continental US; may vary elsewhere.

Storage Conditions

Stored at -20°C for 2 years

Scientific Category

Recombinant Proteins

Available Sizes

Frequently Asked Questions

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