ML264
ML264 is an antitumor agent that potently and selectively inhibits Krüppel-like factor five (KLF5) expression.
Product Specifications
CAS Number
[1550008-55-3]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
KLF
Type
Reference compound
Related Pathways
MAPK/ERK Pathway
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/ML264.html
Purity
98.32
Solubility
DMSO : ≥ 100 mg/mL
Smiles
O=C(NCC(N(C)C(CC1)CCS1(=O)=O)=O)/C=C/C2=CC=CC(Cl)=C2
Molecular Formula
C17H21ClN2O4S
Molecular Weight
384.88
Precautions
H302, H315, H319, H335
References & Citations
[1]Bialkowska A, et al. ML264: An Antitumor Agent that Potently and Selectively Inhibits Krüppel-like Factor Five (KLF5) Expression: A Probe for Studying Colon Cancer Development and Progression.|[2]Ruiz de Sabando A, et al. ML264, A Novel Small-Molecule Compound That Potently Inhibits Growth of Colorectal Cancer. Mol Cancer Ther. 2016 Jan;15 (1) :72-83.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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