Capromorelin (Tartrate)

Capromorelin Tartrate is an orally active, potent growth hormone secretagogue receptor (GHSR) agonist, with Ki of 7 nM for hGHS-R1a.

Product Specifications

CAS Number

[193273-69-7]

Product Name Alternative

CP 424391-18

UNSPSC

12352005

Hazard Statement

H315, H319, H335

Target

GHSR

Type

Reference compound

Related Pathways

GPCR/G Protein

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease; Endocrinology

Assay Protocol

https://www.medchemexpress.com/Capromorelin_Tartrate.html

Purity

98.10

Solubility

DMSO : 100 mg/mL (ultrasonic) |H2O : 100 mg/mL (ultrasonic)

Smiles

O=C([C@@H]([C@@H](O)C(O)=O)O)O.CC(C)(N)C(N[C@H](COCC1=CC=CC=C1)C(N(C[C@]23CC4=CC=CC=C4)CCC2=NN(C)C3=O)=O)=O

Molecular Formula

C32H41N5O10

Molecular Weight

655.70

Precautions

H315, H319, H335

References & Citations

[1]Zollers B, et al. Capromorelin oral solution (ENTYCE?) increases food consumption and body weight when administered for 4 consecutive days to healthy adult Beagle dogs in a randomized, masked, placebo controlled study. BMC Vet Res. 2017 Jan 5;13 (1) :10.|[2]Carpino PA, et al. Pyrazolinone-piperidine dipeptide growth hormone secretagogues (GHSs) . Discovery of capromorelin. Bioorg Med Chem. 2003 Feb 20;11 (4) :581-90.