Fidasimtamab
Product Specifications
UNSPSC Description
Fidasimtamab (IBI-315; BH2950) is a recombinant human IgG1 bispecific antibody that targets, binds and inhibits both HER2 and PD-1 and their downstream signalling pathways, and links PD-1 expressing T cells to HER2 expressing tumour cells. Fidasimtamab has potential immunosuppressive and antitumor activity[1].
Target Antigen
EGFR; PD-1/PD-L1
Type
Inhibitory Antibodies
Related Pathways
Immunology/Inflammation;JAK/STAT Signaling;Protein Tyrosine Kinase/RTK
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/fidasimtamab.html
Purity
95.00
Solubility
10 mM in DMSO
Smiles
[Fidasimtamab]
References & Citations
[1]Shijie Jin, et al. Emerging new therapeutic antibody derivatives for cancer treatment. Signal Transduct Target Ther. 2022 Feb 7;7(1):39.
Shipping Conditions
Dry Ice
Storage Conditions
Store at -80°C for 2 years
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-P99618/Fidasimtamab-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-P99618/Fidasimtamab-SDS-MedChemExpress.pdf
Clinical Information
Phase 2
CAS Number
2377419-89-9
Available Sizes
Curated Selection
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