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Activin A, Human/Mouse/Rat (HEK293, His)

Activin A, a multifunctional cytokine, is a member of TGF-β superfamily. Activin A first binds to the type II activin receptors (ActIIRA or ActRIIB) on the member surface, and then recruits and phosphorylates type I activin receptors (ActRI) . Activin A primarily signal through SMAD2/3 proteins to regulate a variety of functions, including inflammation, fibrosis, and tumorigenesis. Activin A Protein, Mouse (HEK293, His) is produced in HEK293 cells with a C-Terminal His-tag.

Product Specifications

Product Name Alternative

Activin A Protein, Human/Mouse/Rat (HEK293, His), Mouse, HEK293

UNSPSC

12352202

Type

Recombinant Proteins

Related Pathways

Stem Cell/Wnt

Assay Protocol

https://www.medchemexpress.com/cytokines/activin-a-protein-mouse-hek293-his.html

Purity

98.0

Molecular Formula

16323 (Gene_ID) Q3UY39/NP_032406.1 (S21-S424) (Accession)

Molecular Weight

Approximately 18 kDa & 43 kDa, based on SDS-PAGE under reducing conditions, due to the glycosylation.

References & Citations

[1]Ge J, et al. Involvement of CHOP in activin A induced myeloma NS 1 cell apoptosis. Oncol Rep. 2019;42 (6) :2644-2654.|[2]Enrrico Bloise, et al. Activin A in Mammalian Physiology. Physiol Rev. 2019 Jan 1;99 (1) :739-780.

Shipping Conditions

Room temperature in continental US; may vary elsewhere.

Storage Conditions

Stored at -20°C for 2 years

Scientific Category

Recombinant Proteins

Available Sizes

Frequently Asked Questions

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