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(Rac) -S 16924

(Rac) -S 16924 is a partial agonist of the 5-HT1A receptor. (Rac) -S 16924 regulates signaling through its interaction with the 5-HT1A receptor, and (Rac) -S 16924 can stabilize the receptor in its G-protein-coupled conformation without fully activating it, which may affect intracellular signaling pathways associated with this receptor. (Rac) -S 16924 can be used to study the 5-HT1A receptor in mental disorders, especially schizophrenia[1].

Product Specifications

CAS Number

[734513-52-1]

UNSPSC

12352005

Target

5-HT Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/rac-s-16924.html

Smiles

FC1=CC=C(C=C1)C(CC2CN(CC2)CCOC3=C4OCCOC4=CC=C3)=O

Molecular Formula

C22H24FNO4

Molecular Weight

385.43

References & Citations

[1]Newman-Tancredi A, et al. Efficacy of antipsychotic agents at human 5-HT1A receptors determined by [3H] WAY100, 635 binding affinity ratios: relationship to efficacy for G-protein activation[J]. European journal of pharmacology, 2001, 428 (2) : 177-184.

Shipping Conditions

Room temperature

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-106964A/Rac-S-16924-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-106964A/

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

5-HT1 Receptor

Available Sizes

Curated Selection

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