Okanin

Okanin, effective constituent of the flower tea Coreopsis tinctoria, attenuates LPS-induced microglial activation through inhibition of the TLR4/NF-κB signaling pathways[1].

Product Specifications

CAS Number

[484-76-4]

UNSPSC

12352005

Target

NF-κB; Toll-like Receptor (TLR)

Type

Natural Products

Related Pathways

Immunology/Inflammation; NF-κB

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology; Neurological Disease; Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/okanin.html

Concentration

10mM

Purity

99.98

Solubility

DMSO : 16.67 mg/mL (ultrasonic)

Smiles

O=C(C1=CC=C(O)C(O)=C1O)/C=C/C2=CC=C(O)C(O)=C2

Molecular Formula

C15H12O6

Molecular Weight

288.25

References & Citations

[1]Hou Y, et al. Okanin, effective constituent of the flower tea Coreopsis tinctoria, attenuates LPS-induced microglial activation through inhibition of the TLR4/NF-κB signaling pathways. Sci Rep. 2017 Apr 3;7:45705.