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Denintuzumab

Denintuzumab (hBU 12) is a recombinant humanized anti-CD19 monoclonal antibody. Denintuzumab binds to CD19 on the surface of B cells. Denintuzumab can be used as the antibody moiety (ADC antibody) of antibody-drug conjugates to synthesize ADC, Denintuzumab Mafodotin (SGN-CD19A) . Denintuzumab Mafodotin can be used in the research of acute lymphoblastic leukemia[1].

Product Specifications

CAS Number

1630074-14-4

Product Name Alternative

HBU 12

UNSPSC

12352203

Target

ADC Antibody; CD19

Type

Inhibitory Antibodies

Related Pathways

Antibody-drug Conjugate/ADC Related; Immunology/Inflammation

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/denintuzumab.html

Purity

99.0

Solubility

10 mM in DMSO

Smiles

[Denintuzumab]

Molecular Weight

(145.96 kDa)

References & Citations

[1]Farhadfar N, et al. New monoclonal antibodies for the treatment of acute lymphoblastic leukemia. Leuk Res. 2016 Oct;49:13-21.

Shipping Conditions

Dry Ice

Storage Conditions

Store at -80°C for 2 years

Scientific Category

Inhibitory Antibodies

Clinical Information

Phase 2

Available Sizes

Frequently Asked Questions

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