SC-19220
Product Specifications
UNSPSC Description
SC-19220 is a competitive prostaglandinn E2 receptor antagonist. SC-19220 increases the bladder capacity and reduced the voiding efficiency of micturition (elicited by slow transvesical filling) of urethane-anesthetized rats. SC-19220 can restores the balance in bone marrow granulocyte and monocyte production after burn sepsis[1][2].
Target Antigen
Prostaglandin Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
Neuroscience-Neuromodulation
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/sc-19220.html
Purity
99.71
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(N1C2=CC(Cl)=CC=C2OC3=C(C1)C=CC=C3)NNC(C)=O
Molecular Weight
331.75
References & Citations
[1]Maggi CA, et al. The effect of SC-19220, a prostaglandin antagonist, on the micturition reflex in rats. Eur J Pharmacol. 1988 Aug 2;152(3):273-9.|[2]Santangelo S, Shoup M, Gamelli RL, Shankar R. Prostaglandin E2 receptor antagonist (SC-19220) treatment restores the balance to bone marrow myelopoiesis after burn sepsis. J Trauma. 2000 May;48(5):826-30; discussion 830-1.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-102065/SC-19220-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-102065/SC-19220-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
19395-87-0
Available Sizes
Curated Selection
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