α2C adrenoceptor agonist 1

α2C adrenoceptor agonist 1 (Compound A) is an orally active, highly selective, and non-central nervous system penetrating agonist for the α2C-adrenoceptor, with EC50 and Ki values of 108 nM and 12 nM, respectively. α2C adrenoceptor agonist 1 can be used in the study of nasal congestion[1].

Product Specifications

CAS Number

[928115-79-1]

UNSPSC

12352005

Target

Adrenergic Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/α2c-adrenoceptor-agonist-1.html

Solubility

10 mM in DMSO

Smiles

O=C(N(CC)C1=CC=C2OCCN(CC3=CN=CN3)C2=C1)NC

Molecular Formula

C16H21N5O2

Molecular Weight

315.37

References & Citations

[1]Corboz MR, et al. Pharmacological characterization of a novel α2C-adrenoceptor agonist N-[3,4-dihydro-4- (1H-imidazol-4-ylmethyl) -2H-1, 4-benzoxazin-6-yl]-N-ethyl-N'-methylurea (compound A) . J Pharmacol Exp Ther. 2011;337 (1) :256-266.