SOD1-Derlin-1 inhibitor-1
Product Specifications
UNSPSC Description
SOD1-Derlin-1 inhibitor-1 (compound 56-20) is an inhibitor of SOD1-Derlin-1 interaction. SOD1-Derlin-1 inhibitor-1 inhibits SOD1G93A-Derlin-1 complex with an IC50 value of 7.11 μM. SOD1-Derlin-1 inhibitor-1 can be used for the research of amyotrophic lateral sclerosis[1].
Target Antigen
Others
Type
Reference compound
Related Pathways
Others
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/sod1-derlin-1-inhibitor-1.html
Smiles
NC(C1=CC=C(C2=CN=CC=C2)N=C1S3)=C3C(NC(C=CC(Br)=C4)=C4Br)=O
Molecular Weight
504.20
References & Citations
[1]Tsuburaya N, et al. A small-molecule inhibitor of SOD1-Derlin-1 interaction ameliorates pathology in an ALS mouse model. Nat Commun. 2018 Jul 10;9(1):2668.
Shipping Conditions
Room Temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-138131/SOD1-Derlin-1-inhibitor-1-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-138131/SOD1-Derlin-1-inhibitor-1-SDS-MedChemExpress.pdf
CAS Number
840461-03-2
Available Sizes
Curated Selection
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