Pleconaril-d4

Pleconaril-d4 is deuterium labeled Pleconaril.

Product Specifications

CAS Number

[2749329-20-0]

Product Name Alternative

VP 63843-d4; Win 63843-d4

UNSPSC

12352005

Target

Enterovirus; Isotope-Labeled Compounds

Type

Isotope-Labeled Compounds

Related Pathways

Anti-infection; Others

Applications

COVID-19-anti-virus

Field of Research

Infection

Solubility

10 mM in DMSO

Smiles

FC(C1=NC(C2=CC(C)=C(OC([2H])([2H])C([2H])([2H])CC3=CC(C)=NO3)C(C)=C2)=NO1)(F)F

Molecular Formula

C18H14D4F3N3O3

Molecular Weight

385.37

References & Citations

[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216.|[2]Benschop KS, et al. Genetic and antigenic structural characterization for resistance of echovirus 11 to pleconaril in an immunocompromised patient. J Gen Virol. 2015 Mar;96 (Pt 3) :571-9.|[3]Lacroix C, et al. http://www.ncbi.nlm. In vitro characterisation of a pleconaril/pirodavir-like compound with potent activity against rhinoviruses. Virol J. 2015 Jul 14;12:106.