L-Phenylalanine-3-13C
L-Phenylalanine-3-13C is the 13C-labeled L-Phenylalanine. L-Phenylalanine ((S) -2-Amino-3-phenylpropionic acid) is an essential amino acid isolated from Escherichia coli. L-Phenylalanine is a α2δ subunit of voltage-dependent Ca+ channels antagonist with a Ki of 980 nM. L-phenylalanine is a competitive antagonist for the glycine- and glutamate-binding sites of N-methyl-D-aspartate receptors (NMDARs) (KB of 573 μM) and non-NMDARs, respectively. L-Phenylalanine is widely used in the production of food flavors and pharmaceuticals[1][2][3][4].
Product Specifications
CAS Number
[136056-02-5]
Product Name Alternative
(S) -2-Amino-3-phenylpropionic acid-3-13C
UNSPSC
12352005
Target
Calcium Channel; Endogenous Metabolite; iGluR
Type
Isotope-Labeled Compounds
Related Pathways
Membrane Transporter/Ion Channel; Metabolic Enzyme/Protease; Neuronal Signaling
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/l-phenylalanine-3-13c.html
Purity
99.56
Solubility
H2O : 6.67mg/mL (ultrasonic)
Smiles
OC([C@@H](N)[13CH2]C1=CC=CC=C1)=O
Molecular Formula
C8 13CH11NO2
Molecular Weight
166.18
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture and light)
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported
Isoform
NMDA Receptor
Available Sizes
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