Impurity of Doxercalciferol

Impurity of Doxercalciferol is an impurity of doxercalciferol, which is a synthetic analog of ergocalciferol (vitamin D2), used as a agent for secondary hyperparathyroidism and metabolic bone disease, and it suppresses parathyroid synthesis and secretion.

Product Specifications

CAS Number

[127516-23-8]

UNSPSC

12352211

Hazard Statement

H302, H315, H319, H335

Target

VD/VDR

Type

Reference compound

Related Pathways

Vitamin D Related/Nuclear Receptor

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Endocrinology

Assay Protocol

https://www.medchemexpress.com/Impurity-of-Doxercalciferol.html

Purity

96.08

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

C=C([C@H](O)C[C@H](O)C/1)C1=C/C=C2[C@@]3([H])[C@@](CCC/2)(C)[C@]([C@H](C)/C=C/[C@H](C)C(C)C)([H])CC3

Molecular Formula

C28H44O2

Molecular Weight

412.65

Precautions

H302, H315, H319, H335

References & Citations

[1]Duggal J, et al. Involvement of microRNA181a in differentiation and cell cycle arrest induced by a plant-derived antioxidant carnosic acid and vitamin D analog doxercalciferol in human leukemia cells. Microrna. 2012;1 (1) :26-33.