Iso-RJW100
Iso-RJW100 (compound 24-endo) is a dual-liver receptor homologue-1 (LRH-1) and steroidogenic factor-1 (SF-1) agonist with pEC50 of 6.4 and 7.2, respectively[1].
Product Specifications
CAS Number
1276664-61-9
UNSPSC
12352005
Target
Orphan Nuclear Receptor; Orphan Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Vitamin D Related/Nuclear Receptor
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/iso-rjw100.html
Solubility
10 mM in DMSO
Smiles
C=C(C1=CC=CC=C1)[C@]23C(C4=CC=CC=C4)=C(C[C@@]2([H])[C@H](CC3)O)CCCCCC
Molecular Formula
C28H34O
Molecular Weight
386.57
References & Citations
[1]Richard J Whitby, et al. Small molecule agonists of the orphan nuclear receptors steroidogenic factor-1 (SF-1, NR5A1) and liver receptor homologue-1 (LRH-1, NR5A2) . J Med Chem. 2011 Apr 14;54 (7) :2266-81.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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