Iso-RJW100

Iso-RJW100 (compound 24-endo) is a dual-liver receptor homologue-1 (LRH-1) and steroidogenic factor-1 (SF-1) agonist with pEC50 of 6.4 and 7.2, respectively[1].

Product Specifications

CAS Number

[1276664-61-9]

UNSPSC

12352005

Target

Orphan Nuclear Receptor; Orphan Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein; Vitamin D Related/Nuclear Receptor

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/iso-rjw100.html

Solubility

10 mM in DMSO

Smiles

C=C(C1=CC=CC=C1)[C@]23C(C4=CC=CC=C4)=C(C[C@@]2([H])[C@H](CC3)O)CCCCCC

Molecular Formula

C28H34O

Molecular Weight

386.57

References & Citations

[1]Richard J Whitby, et al. Small molecule agonists of the orphan nuclear receptors steroidogenic factor-1 (SF-1, NR5A1) and liver receptor homologue-1 (LRH-1, NR5A2) . J Med Chem. 2011 Apr 14;54 (7) :2266-81.