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GLS-1-IN-1

GLS-1-IN-1 (compound 1d) is a GLS-1 inhibitor. GLS-1-IN-1 shows inhibitory effect against Hep G2, MCF 7, and MCF 10A cells[1].

Product Specifications

UNSPSC

12352005

Target

Glutaminase

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/gls-1-in-1.html

Purity

99.64

Solubility

DMSO : 25 mg/mL (ultrasonic)

Smiles

FC1=CC=C2NC=C(C2=C1)C3=NC(C4=CN(C5=C4C=CC=C5)CCCN6CCOCC6)=CS3

Molecular Formula

C26H25FN4OS

Molecular Weight

460.57

References & Citations

[1]Carbone D, et al. Metabolomics-assisted discovery of a new anticancer GLS-1 inhibitor chemotype from a nortopsentin-inspired library: From phenotype screening to target identification. Eur J Med Chem. 2022;234:114233.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, sealed storage, away from moisture and light)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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