Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

DS-1971a

DS-1971a is a potent, selective, and orally active NaV1.7 inhibitor, with IC50s of 22.8 and 59.4 nM for hNaV1.7 and mNaV1.7, respectively. DS-1971a exerts analgesic effects[1].

Product Specifications

CAS Number

1450595-86-4

UNSPSC

12352005

Hazard Statement

H315-H319-H335

Target

Sodium Channel

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/ds-1971a.html

Purity

99.61

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=S(C1=CC(Cl)=C(O[C@@H]2[C@@H](C3=CC=NN3C)CCCC2)C=C1F)(NC4=NC=NC=C4)=O

Molecular Formula

C20H21ClFN5O3S

Molecular Weight

465.93

Precautions

P261-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P362+P364-P403+P233-P405-P501

References & Citations

[1]Shinozuka T, et al. Discovery of DS-1971a, a Potent, Selective NaV1.7 Inhibitor [published online ahead of print, 2020 May 26]. J Med Chem. 2020;10.1021/acs.jmedchem.0c00259.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

Phase 2

Isoform

Nav1.7

Available Sizes

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

rac 1-Lauroyl-2-oleoyl-3-chloropropanediol
TRC-L184760-25MG 25 mg

rac 1-Lauroyl-2-oleoyl-3-chloropropanediol

Sign In for Pricing
View Details
Human TUBGCP5 activation kit by CRISPRa
GA114456 1 Kit

Human TUBGCP5 activation kit by CRISPRa

Sign In for Pricing
View Details
FRMD3 Human Gene Knockout Kit (CRISPR)
KN419021 1 Kit

FRMD3 Human Gene Knockout Kit (CRISPR)

Sign In for Pricing
View Details
TTF1 (NKX2-1) Mouse Monoclonal Antibody (Biotin conjugated) [Clone ID: OTI3E2]
TA803281AM 100 µL

TTF1 (NKX2-1) Mouse Monoclonal Antibody (Biotin conjugated) [Clone ID: OTI3E2]

Sign In for Pricing
View Details
Steady-LucTM Firefly HTS Assay Kit, 10 x 1000 Assays
#30028-3 1 Kit

Steady-LucTM Firefly HTS Assay Kit, 10 x 1000 Assays

Sign In for Pricing
View Details
NDUFS2 Polyclonal Antibody
E-AB-13445-01 20 µL

NDUFS2 Polyclonal Antibody

Sign In for Pricing
View Details