9-Dihydro-13-acetylbaccatin III

9-Dihydro-13-acetylbaccatin III (9-DHAB III) is an intermediate for the preparation of paclitaxel analogs.

Product Specifications

CAS Number

[142203-65-4]

Product Name Alternative

9-DHAB III; 13-Acetyl-9-dihydrobaccatin III

UNSPSC

12352005

Target

Drug Intermediate

Type

Natural Products

Related Pathways

Others

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/9-dihydro-13-acetylbaccatin-iii.html

Purity

99.62

Solubility

DMSO : 20 mg/mL (ultrasonic)

Smiles

O[C@@H](C1)[C@]2(C)[C@]([C@@]3(OC(C)=O)[C@]1([H])OC3)([H])[C@H](OC(C4=CC=CC=C4)=O)[C@]5(O)C[C@H](OC(C)=O)C(C)=C(C(C)5C)[C@@H](OC(C)=O)[C@@H]2O

Molecular Formula

C33H42O12

Molecular Weight

630.68

References & Citations

[1]Li S, Zhang P, Zhang M, Fu C, Yu L. Functional analysis of a WRKY transcription factor involved in transcriptional activation of the DBAT gene in Taxus chinensis. Plant Biol (Stuttg) . 2013 Jan;15 (1) :19-26.|[2]Naill MC, Kolewe ME, Roberts SC. Paclitaxel uptake and transport in Taxus cell suspension cultures. Biochem Eng J. 2012 Apr 15;63:50-56.|[3]Qayum M, Nisar M, Shah MR, et al. Analgesic and antiinflammatory activities of taxoids from Taxus wallichiana Zucc. Phytother Res. 2012 Apr;26 (4) :552-6.|[4]Kevin Walker and Rodney Croteau. Taxol biosynthesis: Molecular cloning of a benzoyl- CoA:taxane 2α-O-benzoyltransferase cDNA from Taxus and functional expression in Escherichia coli. PNAS, 2000 , 97 (25) : 13591-13596.