Cy5.5 DBCO

Cy5.5 DBCO is a click chemistry reagent containing an cycloalkynes group. Cy5.5 DBCO is a linker of Cyanine5.5 fluorophore. DBCO group enables copper free biocompatible click chemistry with fast reaction kinetics and good stability[1].

Product Specifications

CAS Number

[1857352-95-4]

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

ADC Linker

Type

Reference compound

Related Pathways

Antibody-drug Conjugate/ADC Related

Applications

Cancer-programmed cell death

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/cy5-5-dbco.html

Purity

99.0

Solubility

10 mM in DMSO

Smiles

O=C(CCCCCN1C2=CC=C3C(C=C(S(=O)(O)=O)C=C3S(=O)(O)=O)=C2C(C)(C)/C1=C\C=C\C=C\C4=[N+](CC)C5=C(C4(C)C)C(C=C(S(=O)(O)=O)C=C6S(=O)([O-])=O)=C6C=C5)NCCC(N7C8=C(C#CC9=C(C7)C=CC=C9)C=CC=C8)=O

Molecular Formula

C59H58N4O14S4

Molecular Weight

1175.37

Precautions

H302, H315, H319, H335

References & Citations

[1]Mi Hee Choi, et al. Synthesis and evaluation of an (125) I-labeled azide prosthetic group for efficient and bioorthogonal radiolabeling of cyclooctyne-group containing molecules using copper-free click reaction. Bioorg Med Chem Lett. 2016 Feb 1;26 (3) :875-878.