AcBut
AcBut is a cleavable Ozogamicin linker used in the synthesis of Ozogamicin, a agent-linker conjugate for ADC[1].
Product Specifications
CAS Number
65623-82-7
Product Name Alternative
4- (4-Acetyl-phenoxy) -butyric acid
UNSPSC
12352203
Hazard Statement
H302, H315, H319, H335
Target
ADC Linker
Type
ADC Related
Related Pathways
Antibody-drug Conjugate/ADC Related
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/acbut-1.html
Purity
98.07
Solubility
DMSO : 125 mg/mL (ultrasonic)
Smiles
O=C(O)CCCOC1=CC=C(C(C)=O)C=C1
Molecular Formula
C12H14O4
Molecular Weight
222.24
Precautions
H302, H315, H319, H335
References & Citations
[1]Beck A, et al. Cutting-edge multi-level analytical and structural characterization of antibody-drug conjugates: present and future. Expert Rev Proteomics. 2019;16 (4) :337-362.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, stored under nitrogen)
Scientific Category
ADC Related
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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