[Sar9, Met (O2) 11]-Substance P (TFA)

[Sar9, Met (O2) 11]-Substance P TFA is a tachykinin NK1 receptor selective agonist.

Product Specifications

CAS Number

[2828433-10-7]

UNSPSC

12352209

Target

Neurokinin Receptor

Type

Peptides

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease; Endocrinology

Assay Protocol

https://www.medchemexpress.com/sar9-met-o2-11-substance-p-tfa.html

Purity

98.58

Solubility

H2O : 100 mg/mL (ultrasonic)

Smiles

O=C([C@H]1N(CCC1)C([C@@H](N)CCCNC(N)=N)=O)N[C@@H](CCCCN)C(N2[C@@H](CCC2)C(N[C@@H](CCC(N)=O)C(N[C@@H](CCC(N)=O)C(N[C@H](C(N[C@H](C(N(C)CC(N[C@@H](CC(C)C)C(N[C@H](C(N)=O)CCS(C)(=O)=O)=O)=O)=O)CC3=CC=CC=C3)=O)CC4=CC=CC=C4)=O)=O)=O)=O.O=C(C(F)(F)F)O

Molecular Formula

C66H101F3N18O17S

Molecular Weight

1507.68

References & Citations

[1]Cellier E, et al. Characterization of central and peripheral effects of septide with the use of five tachykinin NK1 receptor antagonists in the rat. Br J Pharmacol. 1999 Jun;127 (3) :717-28.