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Anti-Monkey/Human MDR-1/CD243 Antibody (UIC2)

Anti-Monkey/Human MDR-1/CD243 Antibody (UIC2) is an anti-monkey/human MDR-1/CD243 IgG2a monoclonal antibody. Anti-Monkey/Human MDR-1/CD243 Antibody (UIC2) can efficiently inhibit P-glycoprotein. Anti-Monkey/Human MDR-1/CD243 Antibody (UIC2) enhances the inhibitory effect on multidrug resistance (MDR) by suppressing drug efflux. Anti-Monkey/Human MDR-1/CD243 Antibody (UIC2) can be used for research on cancer[1][2].

Product Specifications

CAS Number

9007-83-4

UNSPSC

12352203

Target

P-glycoprotein

Type

Inhibitory Antibodies

Related Pathways

Membrane Transporter/Ion Channel

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/anti-monkey-human-mdr-1-cd243-antibody-uic2.html

Solubility

10 mM in DMSO

Smiles

[Anti-Monkey/HumanMDR-1/CD243Antibody(UIC2)]

Molecular Weight

(150 kDa)

References & Citations

[1]Goda K, et al. Complete inhibition of P-glycoprotein by simultaneous treatment with a distinct class of modulators and the UIC2 monoclonal antibody. J Pharmacol Exp Ther. 2007 Jan;320 (1) :81-8.|[2]Mechetner EB, et al. Efficient inhibition of P-glycoprotein-mediated multidrug resistance with a monoclonal antibody. Proc Natl Acad Sci U S A. 1992 Jul 1;89 (13) :5824-8.

Shipping Conditions

Room temperature

Scientific Category

Inhibitory Antibodies

Clinical Information

No Development Reported

Frequently Asked Questions

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