PKL-IN-1
PKL-IN-1 is a potent inhibitor of pyruvate kinase (PKL) with an IC50 of 0.07 μM. PKL-IN-1 can be used in the study of non-alcoholic fatty liver disease[1].
Product Specifications
UNSPSC
12352005
Target
Pyruvate Kinase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/pkl-in-1.html
Purity
99.36
Solubility
DMSO : 125 mg/mL (ultrasonic)
Smiles
OC1=C(O)C=C(C(C(O)=C(O)C(O)=C2)=C2OS3(=O)=O)C3=C1
Molecular Formula
C12H8O8S
Molecular Weight
312.25
References & Citations
[1]Matić J, et al. Sulfone-based human liver pyruvate kinase inhibitors - Design, synthesis and in vitro bioactivity. Eur J Med Chem. 2024;269:116306.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
215460 100 µg
Smad 1,2,3,5 (Mothers Against Decapentaplegic Homolog, MAD Homolog, Mothers Against DPP Homolog, JV4-1, Mad-Related Protein, SMAD Family Member, SMAD 1, SMAD 2, SMAD 3, SMAD 5, Smad1, Smad2, Smad3, Smad5, hSMAD1, hSMAD2, hSMAD3, hSMAD5, Transforming Growth Factor-beta-signaling Protein 1, BSP-1, SMAD1, SMAD2, SMAD3, SMAD5, BSP1, MADH1, MADR1, JV18-1, hMAD-2, Mad3, hMAD-3, hMAD-2, MADH2, MADH3, MADH5, JV5-1) discontinued
Ask
View Details 
129784-ML650 100 µL
Moesin (MSN, Membrane-organizing Extension Spike Protein) (MaxLight 650)
Ask
View Details 
