Seletracetam

Seletracetam (Ucb 44212), as an analog of the antiepileptic agent Levetiracetam, is a SV2A modulator for the research of epilepsy[1][2][3].

Product Specifications

CAS Number

[357336-74-4]

Product Name Alternative

Ucb 44212

UNSPSC

12352005

Target

Synaptic Vesicle Proteins

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/seletracetam.html

Concentration

10mM

Purity

99.70

Solubility

DMSO : 200 mg/mL (ultrasonic)

Smiles

O=C([C@@H](N1C(C[C@H](C1)/C=C(F)\F)=O)CC)N

Molecular Formula

C10H14F2N2O2

Molecular Weight

232.23

References & Citations

[1]Pollard JR, et al. Seletracetam, a small molecule SV2A modulator for the treatment of epilepsy. Curr Opin Investig Drugs. 2008 Jan;9 (1) :101-7.|[2]Yang X, et al. Seletracetam enhances short term depression in vitro. Epilepsy Res. 2015 Nov;117:17-22.|[3]Martella G, et al. Seletracetam (ucb 44212) inhibits high-voltage-activated Ca2+ currents and intracellular Ca2+ increase in rat cortical neurons in vitro. Epilepsia. 2009 Apr;50 (4) :702-10.