ACHE-IN-38 (hydrochloride)

ACHE-IN-38 hydrochloride (Compound 13b) inhibits the metabolic breakdown of the neurotransmitter acetylcholine (ACh) by the enzyme acetylcholinesterase (AChE) and hence alleviates memory deficits in patients with Alzheimer’s Disease by potentiating cholinergic transmission[1].

Product Specifications

CAS Number

[120013-39-0]

UNSPSC

12352005

Hazard Statement

H302

Target

Cholinesterase (ChE)

Type

Reference compound

Related Pathways

Neuronal Signaling

Applications

Neuroscience-Neurodegeneration

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/ache-in-38-hydrochloride.html

Purity

99.86

Smiles

O=C1C2=CC(OC)=C(C=C2CC1CC3CCNCC3)OC.Cl

Molecular Formula

C17H24ClNO3

Molecular Weight

325.84

Precautions

H302

References & Citations

[1]Tong W, et al. A comparative molecular field analysis study of N-benzylpiperidines as acetylcholinesterase inhibitors. J Med Chem. 1996 Jan 19;39 (2) :380-7.