ACHE-IN-38 (hydrochloride)
ACHE-IN-38 hydrochloride (Compound 13b) inhibits the metabolic breakdown of the neurotransmitter acetylcholine (ACh) by the enzyme acetylcholinesterase (AChE) and hence alleviates memory deficits in patients with Alzheimer’s Disease by potentiating cholinergic transmission[1].
Product Specifications
CAS Number
120013-39-0
UNSPSC
12352005
Hazard Statement
H302
Target
Cholinesterase (ChE)
Type
Reference compound
Related Pathways
Neuronal Signaling
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/ache-in-38-hydrochloride.html
Purity
99.86
Smiles
O=C1C2=CC(OC)=C(C=C2CC1CC3CCNCC3)OC.Cl
Molecular Formula
C17H24ClNO3
Molecular Weight
325.84
Precautions
H302
References & Citations
[1]Tong W, et al. A comparative molecular field analysis study of N-benzylpiperidines as acetylcholinesterase inhibitors. J Med Chem. 1996 Jan 19;39 (2) :380-7.
Shipping Conditions
Room Temperature
Storage Conditions
Store at room temperature, keep dry and cool
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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