(3R) -3-Pyrrolidinemethanol
(3R) -3-Pyrrolidinemethanol is a molecular building block and the linker of NRX-0492 (HY-153357) .
Product Specifications
CAS Number
[110013-18-8]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
PROTAC Linkers
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/3r-3-pyrrolidinemethanol.html
Purity
99.96
Solubility
DMSO : 175 mg/mL (ultrasonic)
Smiles
OC[C@H]1CNCC1
Molecular Formula
C5H11NO
Molecular Weight
101.15
Precautions
H302, H315, H319, H335
References & Citations
[1]Zhang D, et al. NRX-0492 degrades wild-type and C481 mutant BTK and demonstrates in vivo activity in CLL patient-derived xenografts. Blood. 2023 Mar 30;141 (13) :1584-1596.
Shipping Conditions
Room Temperature
Storage Conditions
RT, protect from light
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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