CL264
CL264 is a TLR7-specific agonist for innate immune signals research[1].
Product Specifications
CAS Number
[1510712-69-2]
UNSPSC
12352005
Target
Toll-like Receptor (TLR)
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/cl264.html
Purity
98.63
Solubility
DMSO : 25 mg/mL (ultrasonic) |H2O : < 0.1 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=C(O)CNC(C1=CC=C(CN2C(NC3=C(N)N=C(NCCCC)N=C23)=O)C=C1)=O
Molecular Formula
C19H23N7O4
Molecular Weight
413.43
References & Citations
[1]Butterfield JSS, et al. TLR9-Activating CpG-B ODN but Not TLR7 Agonists Triggers Antibody Formation to Factor IX in Muscle Gene Transfer. Hum Gene Ther Methods. 2019 Jun;30 (3) :81-92.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
TLR7
Available Sizes
Curated Selection
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