Ferulic acid methyl ester

Ferulic acid methyl ester (Methyl ferulate) is a derivative of ferulic acid, isolated from Stemona tuberosa, with anti-inflammatory and antioxidant properties[1][2]. Ferulic acid methyl ester is a cell membrane and brain permeable compound, shows free radical scavenging ability, used in the research of neurodegenerative disorders[1]. Ferulic acid methyl ester inhibits COX-2 expression, blocks p-p38 and p-JNK in primary bone marrow derived-macrophages[2].

Product Specifications

CAS Number

[2309-07-1]

Product Name Alternative

Methyl ferulate

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Autophagy; p38 MAPK

Type

Natural Products

Related Pathways

Autophagy; MAPK/ERK Pathway

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology; Neurological Disease; Cancer

Assay Protocol

https://www.medchemexpress.com/Ferulic_acid_methyl_ester.html

Purity

99.95

Solubility

DMSO : ≥ 100 mg/mL|H2O : 2 mg/mL (ultrasonic)

Smiles

O=C(/C=C/C1=CC=C(C(OC)=C1)O)OC

Molecular Formula

C11H12O4

Molecular Weight

208.21

Precautions

H302, H315, H319, H335

References & Citations

[1]Sultana R. Ferulic acid ethyl ester as a potential therapy in neurodegenerative disorders. Biochim Biophys Acta. 2012 May;1822 (5) :748-52.|[2]Phuong NT, et al. Anti-inflammatory activity of methyl ferulate isolated from Stemona tuberosa Lour. Asian Pac J Trop Med. 2014 Sep;7S1:S327-31.