Betulinaldehyde

Betulinaldehyde (Betunal) Has anti-cancer and anti-staphylococcus aureus activity. Betulinaldehyde Suppressible Akt, MAPK sum STAT3 Signal path, increase self-transfer, Suppression A549 Cellular vitality, increase and transfer. Betulinaldehyde suppresses PLCγ1/Ca2+/MMP9 signal pathway, has a key effect on vascular plasticity, and is available for cardiovascular disease (CVD) research[1][2][3][4].

Product Specifications

CAS Number

[13159-28-9]

Product Name Alternative

Betulinic aldehyde; Betunal

UNSPSC

12352211

Hazard Statement

H302, H315, H319, H335

Target

Bacterial

Type

Natural Products

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection; Cancer; Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/betulinaldehyde.html

Purity

98.72

Solubility

DMSO : 20 mg/mL (ultrasonic)

Smiles

C=C(C)[C@@H]1CC[C@]2(C=O)CC[C@@]3(C)[C@]4(C)CC[C@@]5([H])C(C)(C)[C@@H](O)CC[C@]5(C)[C@@]4([H])CC[C@]3([H])[C@]21[H]

Molecular Formula

C30H48O2

Molecular Weight

440.70

Precautions

H302, H315, H319, H335

References & Citations

[1]Chung PY, et al. Identification, by gene expression profiling analysis, of novel gene targets in Staphylococcus aureus treated with betulinaldehyde. Res Microbiol. 2013 May;164 (4) :319-26.|[2]Chung PY, et al. Transcriptional profiles of the response of methicillin-resistant Staphylococcus aureus to pentacyclic triterpenoids. PLoS One. 2013;8 (2) :e56687.|[3]Huang PH, et al. Betulinaldehyde exhibits effective anti-tumor effects in A549 cells by regulating intracellular autophagy. Sci Rep. 2023 Jan 13;13 (1) :743.|[4]Fu Y, et al. Betulinaldehyde inhibits vascular remodeling by regulating the microenvironment through the PLCγ1/Ca2+/MMP9 pathway. Phytomedicine. 2023 Jul 25;116:154891.