Isomaculosidine

Isomaculosidine is an alkaloid that can be isolated from D. dasycarpus. Isomaculosidine can inhibit nitric oxide (NO) production in lipopolysaccharide (LPS) -stimulated BV2 microglial cells[1].

Product Specifications

CAS Number

[518-96-7]

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

NO Synthase

Type

Natural Products

Related Pathways

Immunology/Inflammation

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/isomaculosidine.html

Purity

99.42

Solubility

10 mM in DMSO

Smiles

O=C1C2=C(OC=C2)N(C)C3=C1C=C(OC)C=C3OC

Molecular Formula

C14H13NO4

Molecular Weight

259.26

Precautions

H302, H315, H319, H335

References & Citations

[1]Jeong Seon Yoon, et al. Inhibitory alkaloids from Dictamnus dasycarpus root barks on lipopolysaccharide-induced nitric oxide production in BV2 cells. J Enzyme Inhib Med Chem. 2012 Aug;27 (4) :490-4.