Helenalin acetate
Helenalin acetate, a natural NF-κB inhibitor, is a potent C/EBPβ inhibitor. Helenalin acetate has anti-inflammatory and anticancer activities[1].
Product Specifications
CAS Number
[10180-86-6]
UNSPSC
12352005
Target
Histone Demethylase; NF-κB
Type
Reference compound
Related Pathways
Epigenetics; NF-κB
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/helenalin-acetate.html
Purity
99.55
Solubility
10 mM in DMSO
Smiles
CC(O[C@@H]1[C@]2([C@](C=CC2=O)([H])[C@@H](C[C@@H]3[C@H]1C(C(O3)=O)=C)C)C)=O
Molecular Formula
C17H20O5
Molecular Weight
304.34
References & Citations
[1]Jakobs A, et al. Helenalin Acetate, a Natural Sesquiterpene Lactone with Anti-inflammatory and Anti-cancer Activity, Disrupts the Cooperation of CCAAT Box/Enhancer-binding Protein β (C/EBPβ) and Co-activator p300. J Biol Chem. 2016 Dec 9;291 (50) :26098-26108.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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