Dibucaine (hydrochloride)

Dibucaine hydrochloride (Cinchocaine hydrochloride) is a sodium channel inhibitor. Dibucaine hydrochloride is a potent SChE inhibitor[1][2].

Product Specifications

CAS Number

[61-12-1]

Product Name Alternative

Cinchocaine hydrochloride

UNSPSC

12352005

Hazard Statement

H302, H318

Target

Sodium Channel

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/Dibucaine-hydrochloride.html

Concentration

10mM

Purity

99.88

Solubility

DMSO : 110 mg/mL (ultrasonic) |H2O : 100 mg/mL (ultrasonic)

Smiles

O=C(C1=CC(OCCCC)=NC2=CC=CC=C12)NCCN(CC)CC.Cl

Molecular Formula

C20H30ClN3O2

Molecular Weight

379.92

Precautions

H302, H318

References & Citations

[1]Souto-Padron, T., A.P. Lima, and O. Ribeiro Rde, Effects of dibucaine on the endocytic/exocytic pathways in Trypanosoma cruzi. Parasitol Res, 2006. 99 (4) : p. 317-20.|[2]Elamin, B., Dibucaine inhibition of serum cholinesterase. J Biochem Mol Biol, 2003. 36 (2) : p. 149-53.